Progesterone Body Cream is a convenient and effective solution for those who require progesterone as part of their treatment plan. Winona's topical cream contains bioidentical progesterone, which mimics the body's natural hormones and supports overall health and hormonal balance.
Progesterone Body Cream

Progesterone Body Cream

Target 100+ menopause symptoms:
Night sweats & hot flashes
Hormonal weight gain
Low energy & fatigue
Joint & hip pain
Low libido & vaginal dryness
Brain fog
Your prescription includes:
Free, unlimited access to a dedicated doctor
Community events & 24/7 support
Free shipping
Treatment Information
Progesterone plays a vital role in balancing estrogen levels and maintaining endometrial health in menopause. Progesterone Body Cream's simple topical application leads to more stable hormone levels and potentially fewer side effects than oral medications.
Apply the HRT cream topically to clean, dry, and hair-free skin, avoiding the face and breasts. Dispense a pea-sized amount (typically 2 pumps) as directed by your Winona physician.
Massage the cream into your skin for 10-15 seconds until fully absorbed. If the cream beads up, you may have used more than your skin can absorb; consider applying to different areas such as the forearms, abdomen, backs of the knees, or inner thighs.
Wash your hands after application, and allow the cream to absorb for 30 minutes before swimming or bathing.
Active Ingredients:
Progesterone USP
Inactive Ingredients:C12-15 Alkyl Benzoate
Caprylic/Capric Triglycerides
Cetyl Alcohol
Ethylhexylglycerin
Glycerin USP
Glyceryl Stearate
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Oleic Acid
Olive Oil
PEG-100 Stearate
Polymethylsiloxane
Purified Water
Stearic Acid
Trolamine NF
Vitamin E Acetate
All prescription products require an online medical evaluation with a Winona doctor who will determine if a prescription is appropriate.
Promotion of healthy uterine lining
Reduced irregular bleeding
Natural, bioidentical hormones
Fragrance-free
Hypoallergenic
Easy application
Treatment Information
Progesterone plays a vital role in balancing estrogen levels and maintaining endometrial health in menopause. Progesterone Body Cream's simple topical application leads to more stable hormone levels and potentially fewer side effects than oral medications.
Apply the HRT cream topically to clean, dry, and hair-free skin, avoiding the face and breasts. Dispense a pea-sized amount (typically 2 pumps) as directed by your Winona physician.
Massage the cream into your skin for 10-15 seconds until fully absorbed. If the cream beads up, you may have used more than your skin can absorb; consider applying to different areas such as the forearms, abdomen, backs of the knees, or inner thighs.
Wash your hands after application, and allow the cream to absorb for 30 minutes before swimming or bathing.
Active Ingredients:
Progesterone USP
Inactive Ingredients:C12-15 Alkyl Benzoate
Caprylic/Capric Triglycerides
Cetyl Alcohol
Ethylhexylglycerin
Glycerin USP
Glyceryl Stearate
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Oleic Acid
Olive Oil
PEG-100 Stearate
Polymethylsiloxane
Purified Water
Stearic Acid
Trolamine NF
Vitamin E Acetate
All prescription products require an online medical evaluation with a Winona doctor who will determine if a prescription is appropriate.
Promotion of healthy uterine lining
Reduced irregular bleeding
Natural, bioidentical hormones
Fragrance-free
Hypoallergenic
Easy application
Menopause Care Made Easy
Hear how patients are reclaiming their lives with Winona:
How It Works
Winona provides fast, easy, and convenient care for your menopause symptoms.
1—Your easiest visit ever
We’ll gather your medical information and connect you with a Winona physician for personalized recommendations.



Progesterone Body Cream FAQs
Progesterone Body Cream is used for two main reasons: to protect the uterine lining in women taking estrogen, and to help manage symptoms such as poor sleep, anxiety, and mood changes due to its natural calming effects.
At Winona, progesterone is prescribed only when a patient is also using estrogen therapy. Progesterone’s primary role is to protect the uterine lining and balance the effects of estrogen. Although progesterone can have naturally calming effects that support better sleep and mood balance, it’s not prescribed on its own within Winona’s treatment plans.
Yes. The progesterone used in our cream is bioidentical, meaning it’s chemically identical to the hormone naturally produced by the body.
Apply the cream to clean, dry, hair-free skin, avoiding the face and breasts. The inner thighs, forearms, or abdomen are ideal application sites. Progesterone has a calming effect, so applying the cream in the evening can help with sleep.
Many women report improved sleep quality within the first few weeks of consistent use. Other benefits, such as mood stabilization and reduced anxiety, may take one to two months to become more noticeable.
Yes. Data shows that when properly dosed and compounded, progesterone cream can effectively protect the uterine lining and deliver therapeutic levels through the skin.
Progesterone cream is generally well-tolerated. The most common side effect is drowsiness, which is why evening use is recommended. Some women may also experience mild bloating or breast tenderness as their body adjusts. If you have any concerns, or if any side effects persist, please consult your Winona physician.
Each dose is personalized based on your unique needs and health profile, as assessed by a Winona physician.
Yes, progesterone is a prescription-only medication. This ensures a physician can determine the correct dosage for your needs and monitor your treatment over time for safety and effectiveness.
If you miss a dose, apply it as soon as you remember. However, if it’s almost time for your next scheduled dose, skip the missed one and continue your regular routine. Do not apply a double dose.
Yes, our Progesterone Body Cream is formulated without peanut products and is safe for women with peanut allergies.
The bottle may appear less than full, but it contains the exact amount needed for the prescribed doses. Some space is intentionally left for the airless pump mechanism to properly dispense.
You can get your prescription by completing our online onboarding process. This starts with a free intake where you'll answer questions about your health and symptoms. A board-certified doctor will then review your information to determine if you are a candidate for treatment and, if so, will issue a prescription for Progesterone Body Cream.
Once your prescription is issued, there’s a 24-hour review period before the pharmacy begins processing your order. The pharmacy typically prepares your medication within 1–3 business days, followed by shipping, which takes another 1–3 business days. On average, most patients receive their Progesterone Body Cream within about 5 business days.
Your Progesterone Body Cream is delivered directly to your door. Standard shipping is free on all prescriptions. If you need your medication sooner, expedited options are available at checkout, including USPS Priority (2–3 business days) or FedEx Overnight for an additional fee.
While Winona is currently unable to bill insurance companies directly, you can use your HSA (Health Savings Account) or FSA (Flexible Spending Account) card to pay for your Progesterone Body Cream at checkout. You’ll also have access to receipts and documentation that you can use to submit and file a claim with your insurance provider for possible reimbursement.
The active ingredients in your Progesterone Body Cream, such as progesterone USP, are FDA approved. The final medication itself is prepared for you by a state-licensed compounding pharmacy that follows strict quality standards. This allows for personalized dosages not available in pre-packaged, mass-produced medications.
Your treatment is personalized, and ongoing care is included. If you feel your dosage needs adjustment, you can discuss this with your doctor anytime via messaging in the secure Patient Portal. Adjustments are free, and your doctor will work with you to find the right dosage for your needs.
Your Winona subscription includes unlimited, 24/7 messaging with your board-certified doctor. You can ask questions about your Progesterone Body Cream, discuss your symptoms, or request dosage adjustments at any time through the secure Patient Portal.
Your treatment is set up as a subscription, so refills for Progesterone Body Cream are automatically processed and shipped based on your treatment schedule — that way, you never run out. You can manage your subscription, change your shipping date, or cancel at any time.





