Redefining Menopause- What Women Need to Know - Dr. Cat Brown, Medical Director at Winona - Duologue with Leslie
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Duologue with Leslie Heaney: Dr. Cathleen Brown on Redefining Menopause

Published: October, 2025

Dr. Cathleen Brown

Featured Physician

Cathleen M. Brown

Host

Leslie Heaney

Dr. Cathleen Brown, Medical Director at Winona, joined host Leslie Heaney on Duologue just days after World Menopause Awareness Day to unpack what's new in hormone replacement therapy research, including insights from the FDA's July 2025 expert panel on menopause treatment.

The conversation ranges widely — from the lingering fallout of the Women's Health Initiative study to breast cancer risk, bone and heart health, and practical guidance on protein, sleep, and supplements. It's a thorough, myth-busting primer for anyone trying to separate real science from social media noise.


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Episode Details

  • Podcast: Duologue with Leslie Heaney

  • Episode Title: Redefining Menopause: What Women Need to Know - Dr. Cat Brown, Medical Director at Winona

  • Host: Leslie Heaney

  • Guest: Dr. Cathleen Brown

  • Published Date: October 22, 2025

  • Episode Duration: 1 hour 13 minutes

  • Format: Audio & Video Interview

  • Main Topics: HRT, Menopause, Women's Health, Bone Health, Heart Health, Cognitive Health

About Duologue with Leslie Heaney

Duologue with Leslie Heaney (formerly The Interview with Leslie Heaney) features host Leslie Heaney in conversation with experts and thought leaders across health, wellness, fashion, policy, and science. New episodes release every Wednesday.

In this episode, Heaney sits down with Winona's Dr. Cathleen Brown just days after World Menopause Awareness Day to dig into the latest research on hormone therapy, long-term health risks, and practical self-care strategies for midlife.

Visit Duologue with Leslie Heaney.

About This Episode

Dr. Brown opens with a detailed history of why HRT got a "bad rap," tracing the fear back to the Women's Health Initiative study and explaining how the medications used in that study — synthetic, non-bioidentical hormones — don't reflect what's typically prescribed today. She also unpacks findings from the FDA's July 2025 expert panel, including a push to remove the black box warning on vaginal estrogen and growing recognition that heart disease, not breast cancer, is the leading health risk women face after menopause.

From there, the conversation turns practical: how personal (versus family) cancer history affects HRT candidacy, the new non-hormonal medication Veozah for hot flashes, and symptom-by-symptom guidance covering sleep, mood, hair loss, weight gain, joint pain, and skin changes. Dr. Brown closes with concrete recommendations on protein, magnesium, fiber, and resistance training for building a long-term wellness plan.

Topics Covered

  • Why the Women's Health Initiative study caused decades of fear around HRT

  • Findings from the FDA's July 2025 expert panel on menopause treatment

  • Bioidentical versus synthetic hormones and why the distinction matters

  • How personal versus family history of cancer affects HRT candidacy

  • The push to remove the black box warning on vaginal estrogen

  • Veozah, a new non-hormonal option for hot flashes

  • Why heart disease, not breast cancer, is the leading health risk for women

  • Symptom-specific guidance: hot flashes, sleep, mood swings, hair loss, joint pain

  • The connection between weight gain, cortisol, and menopause, including GLP-1 synergy with HRT

  • Protein, magnesium, fiber, and other supplement recommendations for midlife

  • The role of resistance training and weight-bearing exercise in bone health

  • How long women can safely stay on HRT

Key Takeaways

The WHI Study's Synthetic Hormones Don't Reflect Today's HRT

Dr. Brown explains that the Women's Health Initiative study used synthetic, non-bioidentical hormones (conjugated equine estrogens) like Premarin. The initial findings received widespread media attention before the full body of evidence and follow-up analyses were widely understood.

Heart Disease, Not Breast Cancer, Is the Bigger Risk After Menopause

Dr. Brown points out that more women die of heart disease and stroke each year than breast cancer, and that estrogen loss after menopause affects blood vessel health — a risk she says is widely underappreciated compared to breast cancer fears.

Personal Cancer History Matters More Than Family History

Dr. Brown clarifies that having a family member with breast cancer does not automatically disqualify someone from HRT. Still, a personal history of hormone-sensitive cancers like breast, ovarian, or uterine cancer requires a more cautious, individualized conversation with a provider.

Protein Needs Are Higher Than Most Women Realize

Dr. Brown shares that she personally targets 120 grams of protein a day to maintain muscle mass, and notes that most women, when they track their intake, discover they're getting far less than they think — contributing to midlife muscle loss.

Resistance Training and Estrogen Both Protect Bone Health

Dr. Brown explains that weight-bearing and resistance exercise, combined with adequate estrogen levels, are essential for maintaining bone density and preventing the frailty and fracture risk that can follow menopause.


Cathleen M. Brown

Dr. Cathleen M. Brown

Obstetrics & Gynecology

Dr. Cathleen Brown is a menopause specialist and physician with Winona. She brings a physician’s perspective to menopause, perimenopause, hormone changes, symptom care, and treatment options during midlife.

At Winona, Dr. Brown helps women better understand symptoms, health history, hormone changes, and when physician-reviewed care may be appropriate.

Meet Dr. Cathleen M. Brown

Watch or Listen to the Episode

Watch the full conversation with Dr. Cathleen M. Brown on
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