Fluctuating hormones are associated with changes in mood at perimenopause. These variations in hormone levels can cause symptoms similar to premenstrual syndrome (PMS), such as irritability. The impact of other menopause symptoms, as well as stress and lack of sleep during this phase of life, can also contribute to the feeling of irritability.
Relaxing activities and exercise or meditation can help control the changes in your moods. Hormone replacement therapy (HRT) can offer some relief for menopausal mood swings by normalizing the key hormones in the body that play a role in mood. These hormones influence serotonin, a brain chemical that promotes well-being and happiness. When hormone levels drop, serotonin levels also fall, contributing to increased irritability.
HRT can also help regulate cortisol, the stress hormone. High levels of cortisol cause stress and fatigue and can affect your overall health. Built-up stress can further deplete the already decreasing hormones during menopause.